Effectiveness of paliperidone long-acting injection in clinical practice
نویسندگان
چکیده
منابع مشابه
Comparison of Paliperidone Palmitate and Risperidone Long-Acting Injection in Schizophrenic Patients
PURPOSE/BACKGROUND The study objective was to compare the impact of being treated by paliperidone palmitate (PP) or risperidone long-acting injection (RLAI) on the length of stay on initial hospitalization, rehospitalization risk, and treatment duration in schizophrenic patients. METHODS We conducted an observational retrospective cohort study in 43 centers in France, including schizophrenic ...
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OBJECTIVE To review the pharmacokinetics, efficacy, safety, and cost-effectiveness of long-acting risperidone. METHODS Studies published between January 2000 and October 2006 evaluating the pharmacokinetics, efficacy, safety, and cost-effectiveness of long-acting risperidone were reviewed, as identified from literature searches using Medline and EMBASE. Abstracts and posters on long-acting ri...
متن کاملOlanzapine long-acting injection: a review of first experiences of post-injection delirium/sedation syndrome in routine clinical practice
BACKGROUND Olanzapine long-acting injection (LAI) for the treatment of schizophrenia was associated with a cluster of symptoms termed post-injection delirium/sedation syndrome (PDSS) in a small percentage (~2%) of patients during clinical trials. The objective of this analysis was to evaluate the rate and clinical characteristics of PDSS since olanzapine LAI entered commercial use. METHODS Ca...
متن کاملPharmacokinetics of olanzapine long-acting injection: the clinical perspective
Olanzapine long-acting injection (OLAI) is a sustained-release depot antipsychotic for the treatment of schizophrenia in adults. Our objective was to explain the pharmacokinetics of OLAI to provide clinical insight. Simulation models and data from clinical trials are presented. Olanzapine concentrations were observed immediately upon injection. Half-life was ∼30 days, controlled by the slow rat...
متن کاملIncidence of tardive dyskinesia: a comparison of long-acting injectable and oral paliperidone clinical trial databases
BACKGROUND To assess the tardive dyskinesia (TD) rate in studies of once-monthly long-acting injectable (LAI) paliperidone palmitate (PP) and once-daily oral paliperidone extended release (Pali ER). METHODS Completed schizophrenia and bipolar studies for PP and Pali ER (≥ 6 month duration with retrievable patient-level data) were included in this post hoc analysis. Schooler-Kane research crit...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Psychopharmacology
سال: 2018
ISSN: 2045-1253,2045-1261
DOI: 10.1177/2045125317753332